tinnitus

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	169
interventional	154
Observational	14
Registry	1

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Device	51
Behavioral	22
Drug|placebo	20
Other	16
Drug	10
Procedure	9
Behavioral|Other	7
Device|placebo	3
Dietary Supplement|placebo	3
Drug|Other	3
Device|Other	2
Behavioral|Device	1
Behavioral|Device|placebo	1
Biological	1
Dietary Supplement	1
Drug|Procedure	1
Other|placebo	1
placebo|Radiation	1
Radiation	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	52
Germany	27
NA	12
United Kingdom	10
Belgium	8
Brazil	6
France	4
Korea, Republic of	4
Israel	3
Netherlands	3
Turkey	3
China	2
Sweden	2
Switzerland	2
Austria|Germany	1
Austria|Germany|Portugal|Spain|United Kingdom	1
Belgium|Czech Republic|France|Netherlands|Poland|South Africa	1
Czechia	1
Finland	1
Germany|Ireland	1
Germany|Netherlands	1
Greece	1
Hong Kong	1
Ireland	1
Lebanon	1
Spain	1
Taiwan	1
United States|Austria|Brazil|Germany|Mexico	1
United States|Belgium|France	1
United States|Belgium|Germany|Poland	1

Sites per Study

Site_count	Study_Count
1	130
2	7
3	4
4	4
6	2
16	2
18	1
23	1
54	1
56	1
76	1

Phase

Phase	Study_Count
N/A	101
Phase 2	21
Phase 3	10
Phase 4	8
Phase 1/Phase 2	6
Phase 1	4
Early Phase 1	2
Phase 2/Phase 3	2

Number of Arms

Number_of_Arms	Count_of_Studies
1	37
2	85
3	15
4	8
5	1
6	2
NA	6

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	30.00	4.00	10.00	33.00	10.0000	10.0	38.00	40.000
1st Qu.	31.25	30.00	33.25	47.25	40.0000	32.5	178.25	45.250
Median	32.50	50.00	42.50	61.50	70.0000	55.0	371.50	96.000
Mean	32.50	74.86	62.25	55.50	102.2381	55.0	349.80	119.375
3rd Qu.	33.75	100.00	71.50	63.75	126.0000	77.5	444.00	162.500
Max.	35.00	492.00	154.00	70.00	431.0000	100.0	893.00	286.000

Trial Group Type

group_type	Group_Count
Experimental	137
Active Comparator	70
Other	33
Placebo Comparator	33
Sham Comparator	22
No Intervention	6
NA	6

Intervention Model

intervention_model	Study_Count
Parallel Assignment	89
Single Group Assignment	40
Crossover Assignment	24
Sequential Assignment	1

Primary Purpose

primary_purpose	Study_Count
Treatment	140
Supportive Care	4
Other	3
Basic Science	2
Device Feasibility	1
Diagnostic	1
Health Services Research	1
Prevention	1
NA	1

Observational Studies

Studies by Country

Country	Study_Count
United States	6
Brazil	2
Belgium	1
Croatia	1
Ireland	1
NA	1
Switzerland	1
United Kingdom	1

Sites per Study

Site_count	Study_Count
1	12
2	2

Enrollment Metrics

Measure	Observational
Min	17.0000
1st Qu	58.0000
Median	64.0000
Mean	119.6923
3rd Qu	150.0000
Max	403.0000

Observation Model

observational_model	Study_Count
Cohort	7
NA	3
Case-Control	2
Case-Only	2

Time Perspective

time_perspective	Study_Count
Prospective	7
Cross-Sectional	3
Retrospective	2
Other	1
NA	1

Registries

Studies by Country

Country	Study_Count
United States	1

Sites per Study

Site_count	Study_Count
1	1

Enrollment Metrics

Measure	Registries
Min	40
1st Qu	40
Median	40
Mean	40
3rd Qu	40
Max	40

Registry Model

observational_model	Study_Count
Case-Only	1

Time Perspective

time_perspective	Study_Count
Prospective	1

Follow-up

target_duration	Study_Count
6 Weeks	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03365011	Nitrous Oxide Treatment for Tinnitus	https://ClinicalTrials.gov/show/NCT03365011	Completed	Washington University School of Medicine	2017-06-30
NCT03386123	A Comparison of CBTi and Usual Treatment for Tinnitus Related Insomnia	https://ClinicalTrials.gov/show/NCT03386123	Active, not recruiting	University College London Hospitals	2019-12-10
NCT03336398	Investigation of the NMDA Antagonist Ketamine as a Treatment for Tinnitus	https://ClinicalTrials.gov/show/NCT03336398	Recruiting	New York State Psychiatric Institute	2022-12-31
NCT03295890	Dry Needling on the Treatment of Chronic Somatosensory Tinnitus: An Open Pilot Study	https://ClinicalTrials.gov/show/NCT03295890	Recruiting	University of Sao Paulo General Hospital	2018-06-05
NCT03265197	Evaluation of Adding Lidocaine to Dexamethasone in Intra-tympanic Injection for Management of Tinnitus	https://ClinicalTrials.gov/show/NCT03265197	Completed	Kafrelsheikh University	2015-10-31
NCT03218046	EMDR as a Treatment for Tinnitus	https://ClinicalTrials.gov/show/NCT03218046	Completed	Norfolk and Norwich University Hospitals NHS Foundation Trust	2017-08-31
NCT03209297	Temporomandibular Dysfunction in Patients With Tinnitus: Assessment and Treatment	https://ClinicalTrials.gov/show/NCT03209297	Completed	Universiteit Antwerpen	2019-03-30
NCT03114878	The Value of EMDR in the Treatment of Tinnitus	https://ClinicalTrials.gov/show/NCT03114878	Completed	University Hospital, Antwerp	2019-09-30
NCT03101722	Effects of Huperzine A on Presbycusis(Δ,kHz, dB,MMSE, AD)	https://ClinicalTrials.gov/show/NCT03101722	Enrolling by invitation	Fudan University	2021-05-15
NCT03068871	A Comparison of Two Psycho-educational Group Interventions for Tinnitus Patients	https://ClinicalTrials.gov/show/NCT03068871	Completed	Tel-Aviv Sourasky Medical Center	2017-07-23
NCT02974543	Auditory-somatosensory Stimulation to Alleviate Tinnitus	https://ClinicalTrials.gov/show/NCT02974543	Completed	University of Michigan	2016-06-30
NCT02966366	Tinnitus Treatment With Cochlear Implant in Single Sided Deafness	https://ClinicalTrials.gov/show/NCT02966366	Completed	Oticon Medical	2017-03-07
NCT02951715	Improvement of Tinnitus After Oral Zinc on Patients With Noise-induced Hearing Loss	https://ClinicalTrials.gov/show/NCT02951715	Completed	Chang Gung Memorial Hospital	2014-12-31
NCT02850055	Effectiveness of Manual Therapy in Patients With Tinnitus and Temporomandibular Joint Disorder.	https://ClinicalTrials.gov/show/NCT02850055	Completed	Universidad Complutense de Madrid	2018-05-31
NCT02772536	A Clinical Trial Investigating Effect of Tinted Light on Perception of Tinnitus	https://ClinicalTrials.gov/show/NCT02772536	Completed	University of Leicester	2017-12-09
NCT02734576	Venous Sinus Stenting To Treat Intractable Pulsatile Tinnitus Caused By Venous Sinus Stenosis	https://ClinicalTrials.gov/show/NCT02734576	Recruiting	Weill Medical College of Cornell University	2021-01-31
NCT02669069	Treatment Evaluation of Neuromodulation for Tinnitus (TENT-A)	https://ClinicalTrials.gov/show/NCT02669069	Completed	Neuromod Devices Ltd.	2017-07-31
NCT02653547	Influence of Treatment Duration and Stimulation Frequency on rTMS in Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT02653547	Completed	University of Regensburg	2018-05-23
NCT02648542	The Effects of Compensatory Auditory Stimulation and Transcranial Direct Current Stimulation on Tinnitus Perception	https://ClinicalTrials.gov/show/NCT02648542	Completed	Soterix Medical	2014-07-31
NCT02630589	Implantation of an Auditory Brainstem Implant for the Treatment of Incapacitating Unilateral Tinnitus	https://ClinicalTrials.gov/show/NCT02630589	Recruiting	University Medical Center Groningen	2023-01-31
NCT02617953	Objective Diagnosis Method and Efficacy of Repetitive Transcranial Magnetic Stimulation as a Treatment for Tinnitus	https://ClinicalTrials.gov/show/NCT02617953	Enrolling by invitation	Seoul National University Hospital	2020-09-30
NCT02615600	Daily Bitemporal Low-frequency Transcranial Random Noise Stimulation in Tinnitus (tRNS2-tin)	https://ClinicalTrials.gov/show/NCT02615600	Recruiting	University of Regensburg	2020-10-31
NCT02508220	Short-term Effects of Oxytocin Nasal Spray on Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT02508220	Completed	University of Regensburg	2015-11-30
NCT02438891	Internet-based CBT for Tinnitus	https://ClinicalTrials.gov/show/NCT02438891	Recruiting	University of California, Irvine	2020-09-30
NCT02426671	Tinnitus Alleviation Via Sensory Stimulation	https://ClinicalTrials.gov/show/NCT02426671	Completed	National University of Ireland, Maynooth	2012-10-31
NCT02408575	Hearing Aids With “Notched Amplification” for the Treatment of Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT02408575	Completed	University of Regensburg	2016-06-30
NCT02383147	Efficacy Study for Development and Use of Neurofeedback-trainings for Patients Suffering From Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT02383147	Completed	University of Zurich	2017-08-24
NCT02315508	Evaluating Possible Improvement in Tinnitus Severity After 28 Days Dosing of the Study Drug AUT00063 Compared to Placebo	https://ClinicalTrials.gov/show/NCT02315508	Completed	Autifony Therapeutics Limited	2015-12-31
NCT02306447	Combined Transcranial and Peripheral Muscle Magnetic Stimulation in Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT02306447	Completed	University of Regensburg	2016-04-30
NCT02293512	A Comparison of Three Psychoeducational Group Interventions for Veterans With Tinnitus	https://ClinicalTrials.gov/show/NCT02293512	Completed	VA Office of Research and Development	2016-08-31
NCT02290015	Acupuncture as a Treatment for Tinnitus	https://ClinicalTrials.gov/show/NCT02290015	Completed	Federal University of São Paulo	2013-09-30
NCT02285803	The Effect of Transcranial Direct Current Stimulation (tDCS) in Addition to Tinnitus Retraining Therapy (TRT) for Treatment of Chronic Tinnitus Patients	https://ClinicalTrials.gov/show/NCT02285803	Completed	University Hospital, Antwerp	2016-03-31
NCT02269839	A Feasibility Study Assessing the Effectiveness of rTMS in Tinnitus	https://ClinicalTrials.gov/show/NCT02269839	Completed	Sheffield Teaching Hospitals NHS Foundation Trust	2016-06-30
NCT02266160	Treating Tinnitus Using Eutectic Mixture of Local Anesthetics (EMLA) 5% Cream	https://ClinicalTrials.gov/show/NCT02266160	Completed	HaEmek Medical Center, Israel	2015-11-30
NCT02199106	Effectiveness of Neuronavigated Continuous Theta Burst Stimulation of the Left Heschl’s Gyrus in Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT02199106	Completed	University of Regensburg	2011-03-31
NCT02095262	Gameplay as a Source of Intrinsic Motivation in a Randomized Controlled Trial of Auditory Training for Tinnitus	https://ClinicalTrials.gov/show/NCT02095262	Completed	Nottingham University Hospitals NHS Trust	2012-04-30
NCT02088866	Commercial Lidocaine Patch as a Treatment for Ear-ringing	https://ClinicalTrials.gov/show/NCT02088866	Completed	University of California, Davis	2015-08-31
NCT02071732	Therapeutic Effect of Repetitive Transcranial Magnetic Stimulaton on Tinnitus	https://ClinicalTrials.gov/show/NCT02071732	Recruiting	Dongtan Sacred Heart Hospital	2028-12-31
NCT02062333	The Effects of the Drugs Used in Hypotensive Anaesthesia on Cochlea	https://ClinicalTrials.gov/show/NCT02062333	Completed	TC Erciyes University	2014-11-30
NCT02059447	A Comparison of the Benefits of Mindfulness Based Cognitive Therapy, Relaxation Therapy and a Waiting List Control in the Management of Distress in Chronic Tinnitus Patients	https://ClinicalTrials.gov/show/NCT02059447	Completed	University College London Hospitals	2015-12-31
NCT01302873	Study of BGG492 in Patients With Chronic Subjective Tinnitus	https://ClinicalTrials.gov/show/NCT01302873	Completed	Novartis	2012-01-31
NCT01273883	A Trial of Magnesium Dependent Tinnitus	https://ClinicalTrials.gov/show/NCT01273883	Completed	Mayo Clinic	2013-10-31
NCT01270282	Comparison of Single Versus Repeat Doses of AM-101 in the Treatment of Acute Inner Ear Tinnitus	https://ClinicalTrials.gov/show/NCT01270282	Completed	Auris Medical, Inc.	2013-05-31
NCT02040194	AM-101 in the Treatment of Acute Tinnitus 3	https://ClinicalTrials.gov/show/NCT02040194	Completed	Auris Medical, Inc.	2017-12-28
NCT01988688	Pilot Study of Deep Brain Stimulation (DBS) in Area LC for Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT01988688	Completed	University of California, San Francisco	2019-03-31
NCT01962558	Vagus Nerve Stimulation (VNS) Paired With Tones for Tinnitus	https://ClinicalTrials.gov/show/NCT01962558	Completed	MicroTransponder Inc.	2015-05-31
NCT01944501	Neuromodulation Techniques in the Treatment of Chronic Tinnitus With Hearing Loss	https://ClinicalTrials.gov/show/NCT01944501	Completed	University of Brasilia	2012-12-31
NCT01934010	AM-101 in the Treatment of Post-Acute Tinnitus 1	https://ClinicalTrials.gov/show/NCT01934010	Completed	Auris Medical, Inc.	2017-01-31
NCT01929837	Tinnitus rTMS 2013	https://ClinicalTrials.gov/show/NCT01929837	Completed	Turku University Hospital	2016-08-31
NCT01927991	Internet-based Self-help for Tinnitus: The Role of Support	https://ClinicalTrials.gov/show/NCT01927991	Completed	Philipps University Marburg Medical Center	2013-12-31
NCT01886092	Repetitive Transcranial Magnetic Stimulation as a Treatment for Tinnitus	https://ClinicalTrials.gov/show/NCT01886092	Enrolling by invitation	Seoul National University Hospital	2019-09-30
NCT01857661	The Influence of the Sound Generator Combined With Conventional Amplification for Tinnitus Control: Blind Randomized Clinical Trial	https://ClinicalTrials.gov/show/NCT01857661	Completed	University of Sao Paulo	2013-04-30
NCT01845155	Neuro-Music-Therapy for Patients With Chronic Tinnitus - a Controlled Clinical Trial	https://ClinicalTrials.gov/show/NCT01845155	Completed	German Center for Music Therapy Research	2013-01-31
NCT01803646	AM-101 in the Treatment of Acute Tinnitus 2	https://ClinicalTrials.gov/show/NCT01803646	Completed	Auris Medical, Inc.	2016-06-30
NCT01663324	rTMS for the Treatment of Chronic Tinnitus: Optimization by Simulation of the Cortical Tinnitus Network	https://ClinicalTrials.gov/show/NCT01663324	Completed	University of Regensburg	2014-08-31
NCT01663311	Repetitive Transcranial Magnetic Stimulation With Double Cone Coil in Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT01663311	Completed	University of Regensburg	2013-06-30
NCT01590264	rTMS Bimodal Treatment For Tinnitus: A Pilot Study	https://ClinicalTrials.gov/show/NCT01590264	Completed	Washington University School of Medicine	2012-09-30
NCT01550796	Treatment of Chronic Bothersome Tinnitus Using Cognitive Training and D-cycloserine	https://ClinicalTrials.gov/show/NCT01550796	Completed	Washington University School of Medicine	2012-04-30
NCT01549145	Sub-chronic Neurostimulation Delivered in the Middle Ear for Tinnitus Suppression	https://ClinicalTrials.gov/show/NCT01549145	Completed	EstimME Ltd.	2011-04-30
NCT01541969	Evaluation of the CR Neuromodulation Treatment for Tinnitus	https://ClinicalTrials.gov/show/NCT01541969	Completed	Nottingham University Hospitals NHS Trust	2014-02-28
NCT01487447	Customized Acoustic Stimulation for the Treatment of Tinnitus	https://ClinicalTrials.gov/show/NCT01487447	Completed	University of California, Irvine	2015-01-31
NCT01480193	New Therapy for Patients With Severe Tinnitus	https://ClinicalTrials.gov/show/NCT01480193	Completed	Duke University	2013-11-30
NCT01458821	Cognitive Training for Firefighters With Tinnitus	https://ClinicalTrials.gov/show/NCT01458821	Completed	Washington University School of Medicine	2014-01-31
NCT01435317	Acoustic Coordinated Reset (CR®) Neuromodulation for the Treatment of Chronic Tonal Tinnitus (“RESET Real Life”)	https://ClinicalTrials.gov/show/NCT01435317	Completed	ANM Adaptive Neuromodulation GmbH	2013-06-30
NCT01407133	Conventional Repetitive Transcranial Magnetic Stimulation for Tinnitus Treatment	https://ClinicalTrials.gov/show/NCT01407133	Completed	Hospices Civils de Lyon	2009-09-30
NCT01378650	A Study on the Effect of Cilostazol in Patients With Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT01378650	Completed	Asan Medical Center	2013-06-30
NCT04404439	Treatment of Tinnitus With Migraine Medications	https://ClinicalTrials.gov/show/NCT04404439	Recruiting	University of California, Irvine	2022-09-30
NCT04402593	Music Therapy For The Treatment Of Cisplatin Induced Tinnitus In Patients With rGCC: A Pilot Study	https://ClinicalTrials.gov/show/NCT04402593	Active, not recruiting	Indiana University	2021-12-31
NCT04335929	Internet-based Cognitive Behavioural Therapy for Spanish Tinnitus Sufferers	https://ClinicalTrials.gov/show/NCT04335929	Active, not recruiting	Lamar University	2021-07-03
NCT04335812	Internet-based Cognitive Behavioral Therapy for Tinnitus Sufferers	https://ClinicalTrials.gov/show/NCT04335812	Active, not recruiting	Lamar University	2021-08-31
NCT04262050	Combined tDCS and TMS on Subjective Tinnitus and Combined Depression	https://ClinicalTrials.gov/show/NCT04262050	Completed	Seoul National University Hospital	2018-07-01
NCT04210310	High Dose Oxytocin Nasal Spray for Treatment of Tinnitus	https://ClinicalTrials.gov/show/NCT04210310	Recruiting	NYU Langone Health	2020-06-30
NCT04127708	Tinnitus and Acupuncture	https://ClinicalTrials.gov/show/NCT04127708	Completed	Aksaray University Training and Research Hospital	2019-03-16
NCT04069364	Systematic Assessment of Self-help Tools for the Management of Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT04069364	Recruiting	University Hospital Regensburg	2019-12-31
NCT04004260	CBT-based Internet Intervention for Adults With Tinnitus in the United States	https://ClinicalTrials.gov/show/NCT04004260	Active, not recruiting	Lamar University	2021-08-31
NCT03918109	OTO-313 in Subjects With Subjective Tinnitus	https://ClinicalTrials.gov/show/NCT03918109	Completed	Otonomy, Inc.	2020-05-29
NCT03904264	Feasibility and Acceptability of Using Low-Gain Hearing Aids for Bothersome Tinnitus	https://ClinicalTrials.gov/show/NCT03904264	Recruiting	VA Office of Research and Development	2021-01-01
NCT03895047	ICCAC-ToNF & Tinnitus	https://ClinicalTrials.gov/show/NCT03895047	Recruiting	University of Zurich	2020-08-31
NCT03888521	Evaluating the GN ReSound Relief App Using task-and Rest-based fMRI	https://ClinicalTrials.gov/show/NCT03888521	Active, not recruiting	University of Illinois at Urbana-Champaign	2019-12-03
NCT03802513	Somatosensory Tinnitus Study	https://ClinicalTrials.gov/show/NCT03802513	Recruiting	VA Office of Research and Development	2021-03-31
NCT03782220	Effects of Kinesio Taping in Patients With Somatosensory Tinnitus	https://ClinicalTrials.gov/show/NCT03782220	Completed	Hitit University	2018-04-18
NCT03764826	Study on the Effect of Sound Therapy on Chronic Primary Tinnitus	https://ClinicalTrials.gov/show/NCT03764826	Recruiting	Beijing Friendship Hospital	2019-06-08
NCT03759834	Cochlear Promontory Stimulation for Treatment of Tinnitus	https://ClinicalTrials.gov/show/NCT03759834	Active, not recruiting	Mayo Clinic	2021-12-01
NCT03754127	A Randomized Controlled HD-tDCS Trial: Effects on Tinnitus Severity and Cognition	https://ClinicalTrials.gov/show/NCT03754127	Recruiting	University Hospital, Antwerp	2021-09-30
NCT03716544	Efficacy of Amplification With Hearing Aids for Tinnitus Relief	https://ClinicalTrials.gov/show/NCT03716544	Recruiting	Education University of Hong Kong	2020-09-30
NCT03711630	Impact of Meditation on Bothersome Tinnitus	https://ClinicalTrials.gov/show/NCT03711630	Completed	State University of New York at Buffalo	2019-02-23
NCT03702166	Network Dysregulation Among Individuals With Comorbid Tinnitus and PTSD	https://ClinicalTrials.gov/show/NCT03702166	Recruiting	The University of Texas Health Science Center at San Antonio	2020-05-30
NCT03699826	Experimental Tinnitus Treatment With Transcranial Magnetic Stimulation	https://ClinicalTrials.gov/show/NCT03699826	Enrolling by invitation	University of Iowa	2023-12-31
NCT03688113	Tinnitus Treatment Using a Smartphone Application	https://ClinicalTrials.gov/show/NCT03688113	Completed	Tel-Aviv Sourasky Medical Center	2019-12-01
NCT03657615	Hearing Aid Impact on Chronic Tinnitus Patients Evaluated by Resting State PET.	https://ClinicalTrials.gov/show/NCT03657615	Recruiting	University of Sao Paulo General Hospital	2018-09-30
NCT03632512	Effect of Hericium Erinaceus on Clinical Patients With Hearing Impairment	https://ClinicalTrials.gov/show/NCT03632512	Recruiting	Providence University, Taiwan	2019-01-17
NCT03621735	Reversing Synchronized Brain Circuits With Targeted Auditory-Somatosensory Stimulation to Treat Phantom Percepts	https://ClinicalTrials.gov/show/NCT03621735	Enrolling by invitation	University of Michigan	2022-09-30
NCT03550430	Neurofeedback for Tinnitus - Does Frequency Specificity Matter?	https://ClinicalTrials.gov/show/NCT03550430	Recruiting	Philipps University Marburg Medical Center	2020-06-01
NCT03544359	MRI Study of Noninvasive Transcranial Electrical Stimulation in Tinnitus	https://ClinicalTrials.gov/show/NCT03544359	Recruiting	Northwestern University	2021-08-31
NCT03530306	Treatment Evaluation of Neuromodulation for Tinnitus - Stage A2	https://ClinicalTrials.gov/show/NCT03530306	Completed	Neuromod Devices Ltd.	2018-10-02
NCT03511807	Acoustic and Electrical Stimulation for the Treatment of Tinnitus	https://ClinicalTrials.gov/show/NCT03511807	Recruiting	University of California, Irvine	2021-01-01
NCT03425045	Repetitive Transcranial Magnetic Stimulation for Chronic Subjective Tinnitus	https://ClinicalTrials.gov/show/NCT03425045	Completed	University Hospital Ostrava	2018-03-31
NCT01268449	Evaluation of Low Dose Laser in Treatment of Tinnitus	https://ClinicalTrials.gov/show/NCT01268449	Completed	Islamic Azad University of Mashhad	2010-08-31
NCT01261949	Combined Low Frequency Frontal and Temporal rTMS Treatment in Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT01261949	Completed	University of Regensburg	2010-12-31
NCT01253616	Proof-of-Concept Study Assessing VNS Paired With Tones for Tinnitus	https://ClinicalTrials.gov/show/NCT01253616	Completed	MicroTransponder Inc.	2012-02-29
NCT01229709	Mindfulness Based Tinnitus Reduction (MBTR): A Symptom Perception Shift Program	https://ClinicalTrials.gov/show/NCT01229709	Completed	University of California, San Francisco	2011-06-30
NCT01226108	The Akloma Tinnitus Patch in Patients With Manifested Tinnitus	https://ClinicalTrials.gov/show/NCT01226108	Completed	Akloma Bioscience AB	2011-08-31
NCT01205919	Internet-based Guided Self-help for Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT01205919	Completed	Johannes Gutenberg University Mainz	2010-10-31
NCT01205906	Comparison of an Internet-based Guided Self-help and a Group Therapy for Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT01205906	Completed	Johannes Gutenberg University Mainz	2011-03-31
NCT01177137	Tinnitus Retraining Therapy Trial	https://ClinicalTrials.gov/show/NCT01177137	Completed	Johns Hopkins Bloomberg School of Public Health	2017-02-28
NCT01176734	The Treatment of Tinnitus With Transcutaneous Non-invasive Vagus Nerve Stimulation	https://ClinicalTrials.gov/show/NCT01176734	Completed	cerbomed GmbH	2012-07-31
NCT01129141	Telephone Tinnitus Education for Patients With Traumatic Brain Injury (TBI)	https://ClinicalTrials.gov/show/NCT01129141	Completed	VA Office of Research and Development	2015-09-30
NCT01104207	Transcranial Magnetic Stimulation for Tinnitus	https://ClinicalTrials.gov/show/NCT01104207	Completed	VA Office of Research and Development	2016-12-31
NCT01015781	Multi-Site Evaluation of Progressive Tinnitus Management	https://ClinicalTrials.gov/show/NCT01015781	Completed	VA Office of Research and Development	2013-12-31
NCT00999648	Efficacy of Myofascial Trigger Point Pressure Release on Tinnitus Patients	https://ClinicalTrials.gov/show/NCT00999648	Completed	University of Sao Paulo General Hospital	2009-09-30
NCT00955799	Efficacy, Safety, Tolerability of Neramexane in Patients With Subjective Tinnitus	https://ClinicalTrials.gov/show/NCT00955799	Completed	Merz Pharmaceuticals GmbH	2011-05-31
NCT00927121	Clinical Investigation on the Acoustic Stimulation in the Treatment of Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT00927121	Completed	ANM Adaptive Neuromodulation GmbH	NA
NCT00926237	Effect of rTMS on Resting State Brain Activity in Tinnitus	https://ClinicalTrials.gov/show/NCT00926237	Recruiting	University of Arkansas	2020-09-30
NCT00916305	TUNE! Teaching the UK About Noise Exposure: A Pilot Study	https://ClinicalTrials.gov/show/NCT00916305	Completed	London School of Hygiene and Tropical Medicine	2009-10-31
NCT00886938	rTMS To The Dorsolateral Prefrontal Cortex For Patients With Subjective Idiopathic Tinnitus. A Pilot Study	https://ClinicalTrials.gov/show/NCT00886938	Completed	Washington University School of Medicine	2010-08-31
NCT00876720	Effectiveness Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT00876720	Completed	University of Regensburg	2010-08-31
NCT00860808	Efficacy of AM 101 in Patients With Acute Inner Ear Tinnitus	https://ClinicalTrials.gov/show/NCT00860808	Completed	Auris Medical, Inc.	2011-05-31
NCT00841230	Deanxit and Rivotril in Tinnitus Patients	https://ClinicalTrials.gov/show/NCT00841230	Completed	University Hospital, Antwerp	2009-07-31
NCT01907022	Combined rTMS and Relaxation in Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT01907022	Completed	University of Regensburg	2014-07-31
NCT00833950	Phase Out in Tinnitus Patients	https://ClinicalTrials.gov/show/NCT00833950	Completed	University Hospital, Antwerp	2009-03-31
NCT03773926	Neuro-feedback Therapy for Treating Tinnitus	https://ClinicalTrials.gov/show/NCT03773926	Recruiting	Zeta Technologies	2019-01-15
NCT03022084	Clinical Trial of Sound-Based Versus Behavioral Therapy for Tinnitus	https://ClinicalTrials.gov/show/NCT03022084	Completed	VA National Center for Rehabilitative Auditory Research	2019-06-30
NCT02040207	AM-101 in the Treatment of Post-Acute Tinnitus 2	https://ClinicalTrials.gov/show/NCT02040207	Completed	Auris Medical, Inc.	2016-12-31
NCT02016313	The Effect of Physiotherapy on Cervicogenic Somatic Tinnitus	https://ClinicalTrials.gov/show/NCT02016313	Completed	Universiteit Antwerpen	2014-08-31
NCT01965028	Daily Bi-temporal Transcranial Random Noise Stimulation in Tinnitus	https://ClinicalTrials.gov/show/NCT01965028	Completed	University of Regensburg	2016-01-31
NCT01540357	Mindfulness-based Therapy in Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT01540357	Completed	University of Regensburg	2010-10-31
NCT02737670	Sulodexide Efficacy in Chronic Idiopathic Subjective Tinnitus	https://ClinicalTrials.gov/show/NCT02737670	Completed	St Joseph University, Beirut, Lebanon	2017-03-31
NCT01855425	Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose	https://ClinicalTrials.gov/show/NCT01855425	Completed	Carestream Health, Inc.	2013-08-09
NCT04105426	A Study on the Effectiveness of Antioxidant Supplementation in Tinnitus	https://ClinicalTrials.gov/show/NCT04105426	Completed	National and Kapodistrian University of Athens	2019-05-25
NCT00772980	Efficacy, Safety and Tolerability of Neramexane in Comparison to Placebo in Patients With Subjective Tinnitus	https://ClinicalTrials.gov/show/NCT00772980	Completed	Merz Pharmaceuticals GmbH	2010-06-30
NCT00748475	Countering Stimulus-Induced Alpha-Desynchronization to Treat Tinnitus	https://ClinicalTrials.gov/show/NCT00748475	Completed	University of Konstanz	2010-05-31
NCT00739635	Efficacy, Safety and Tolerability of Neramexane in Patients With Subjective Tinnitus	https://ClinicalTrials.gov/show/NCT00739635	Completed	Merz Pharmaceuticals GmbH	2010-02-28
NCT00733044	Cost-effectiveness of Multidisciplinary Management of Tinnitus	https://ClinicalTrials.gov/show/NCT00733044	Completed	Maastricht University Medical Center	2011-11-30
NCT00724152	Cognitive Behavioral Therapy (CBT) for Tinnitus	https://ClinicalTrials.gov/show/NCT00724152	Completed	VA Office of Research and Development	2011-02-28
NCT00719940	Tinnitus Treatment by Structured Cognitive Behavioral Therapy	https://ClinicalTrials.gov/show/NCT00719940	Completed	University Hospital Tuebingen	2004-10-31
NCT00683644	Zinc to Treat Tinnitus in the Elderly	https://ClinicalTrials.gov/show/NCT00683644	Completed	University of Iowa	2011-12-31
NCT00668720	Repetitive Transcranial Magnetic Stimulation (rTMS) for Tinnitus	https://ClinicalTrials.gov/show/NCT00668720	Completed	UMC Utrecht	2011-06-30
NCT00666809	Vardenafil in Tinnitus	https://ClinicalTrials.gov/show/NCT00666809	Completed	Bayer	NA
NCT00628316	Effects of Caffeine in Tinnitus	https://ClinicalTrials.gov/show/NCT00628316	Completed	Faculdade de Medicina de Valenca	2008-09-30
NCT00596531	Clinical Trial of Acamprosate for Tinnitus	https://ClinicalTrials.gov/show/NCT00596531	Completed	Oregon Health and Science University	2013-11-30
NCT00578058	Randomized Trial Of Tinnitus Retraining Therapy	https://ClinicalTrials.gov/show/NCT00578058	Completed	University of Iowa	2009-11-30
NCT00518024	Safety and Effectiveness of Repetitive Transcranial Magnetic Stimulation in the Treatment of Tinnitus	https://ClinicalTrials.gov/show/NCT00518024	Completed	University Hospital Tuebingen	NA
NCT00486577	Chronic Electrical Stimulation of the Auditory Cortex for Intractable Tinnitus	https://ClinicalTrials.gov/show/NCT00486577	Completed	University Hospital, Bordeaux	2010-12-31
NCT00405886	Neramexane for Tinnitus	https://ClinicalTrials.gov/show/NCT00405886	Completed	Merz Pharmaceuticals GmbH	2007-03-31
NCT00397007	Psychophysiological Treatment of Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT00397007	Completed	Philipps University Marburg Medical Center	NA
NCT00394056	Vestipitant Or Vestipitant/Paroxetine Combination In Subjects With Tinnitus And Hearing Loss.	https://ClinicalTrials.gov/show/NCT00394056	Completed	GlaxoSmithKline	2009-08-31
NCT00371436	Progressive Intervention Program for Tinnitus Management	https://ClinicalTrials.gov/show/NCT00371436	Completed	VA Office of Research and Development	2009-09-30
NCT00329524	Using PET-CT to Target and Validate Low-frequency TMS as Treatment for Tinnitus	https://ClinicalTrials.gov/show/NCT00329524	Completed	University of Arkansas	2008-06-30
NCT00257270	The Effect of Gabapentin on the Sensation and Impact of Tinnitus	https://ClinicalTrials.gov/show/NCT00257270	Completed	Tinnitus Research Consortium	NA
NCT00235807	Multi-Site Randomized Clinical Study of Tinnitus Treatment Methods	https://ClinicalTrials.gov/show/NCT00235807	Completed	VA Office of Research and Development	2006-11-30
NCT00124800	The Effect of Tinnitus Retraining Therapy on Subjective and Objective Measures of Chronic Tinnitus	https://ClinicalTrials.gov/show/NCT00124800	Completed	Tinnitus Research Consortium	2009-06-30
NCT00591994	Tinnitus Treatment With Piribedil Guided by Acoustic Otoemissions and Electrocochleography	https://ClinicalTrials.gov/show/NCT00591994	Completed	Faculdade de Medicina de Valenca	2007-12-31
NCT00567892	Collaborative Tinnitus Research at Washington University	https://ClinicalTrials.gov/show/NCT00567892	Completed	Washington University School of Medicine	2011-06-30
NCT00013390	Evaluation of Treatment Methods for Clinically Significant Tinnitus	https://ClinicalTrials.gov/show/NCT00013390	Completed	VA Office of Research and Development	2002-09-30

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT02570048	1 Tinnitus Alleviation Via Sensory Substitution	https://ClinicalTrials.gov/show/NCT02570048	Completed	MuteButton	2013-05-31
NCT01294124	Investigating the Neurobiology of Tinnitus	https://ClinicalTrials.gov/show/NCT01294124	Completed	Washington University School of Medicine	2019-07-12
NCT01837368	Research Project About Psychological Strain, Quality of Life and Emotional Awareness in Patients With Tinnitus	https://ClinicalTrials.gov/show/NCT01837368	Completed	University of Zurich	2016-05-31
NCT01395368	Cognitive Speed as an Objective Measure of Tinnitus	https://ClinicalTrials.gov/show/NCT01395368	Completed	Washington University School of Medicine	2011-10-31
NCT04310605	Effectiveness of Specialised Cognitive Behavioural Therapy (CBT) for Tinnitus.	https://ClinicalTrials.gov/show/NCT04310605	Completed	Maastricht University	2016-11-16
NCT04281953	Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors	https://ClinicalTrials.gov/show/NCT04281953	Completed	University of Nottingham	2020-02-28
NCT04162405	Tinnitus in Patients With and Without Sensorineural Hearing Loss	https://ClinicalTrials.gov/show/NCT04162405	Recruiting	University Hospital “Sestre Milosrdnice”	2020-06-30
NCT01222507	Processing Speed as an Objective Measure of Tinnitus	https://ClinicalTrials.gov/show/NCT01222507	Completed	Washington University School of Medicine	2010-10-31
NCT01187251	Incidence of Tinnitus Amongst Teenagers and Young Adults mp3 Users	https://ClinicalTrials.gov/show/NCT01187251	Completed	Faculdade de Medicina de Valenca	2009-12-31
NCT00976547	Correlation Analysis of Hearing Thresholds, Validated Questionnaires and Psychoacoustic Measurements in Tinnitus Patients	https://ClinicalTrials.gov/show/NCT00976547	Completed	Faculdade de Medicina de Valenca	2009-05-31
NCT00973648	Exploring Voluntary Control of Tinnitus	https://ClinicalTrials.gov/show/NCT00973648	Completed	Washington University School of Medicine	2010-08-31
NCT00878696	Influence of Tonic and Burst Transcranial Magnetic Stimulation (TMS) Characteristics on Acute Inhibition of Subjective Tinnitus	https://ClinicalTrials.gov/show/NCT00878696	Completed	University Hospital, Antwerp	2007-09-30
NCT00359931	Brain Imaging of Tinnitus	https://ClinicalTrials.gov/show/NCT00359931	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00018486	Epidemiology of Hearing Loss in Diabetic and Non-Diabetic Veterans	https://ClinicalTrials.gov/show/NCT00018486	Completed	VA Office of Research and Development	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT02191592	EMA-Defined Tinnitus Subgroups	https://ClinicalTrials.gov/show/NCT02191592	Completed	Washington University School of Medicine	2015-07-31